Name: B-hCCL11 mice
Brand: Biocytogen
SKU: 111404

B-hCCL11 mice

Catalog Number: 111404

Strain Name: C57BL/6N-Ccl11^{tm1(CCL11)Bcgen}/Bcgenn

Strain Background: C57BL/6N

NCBI gene ID: 6356 (Human)

Aliases: SCYA11

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Targeting strategy

Gene targeting strategy for B-hCCL11 mice. The exons 1-3 of mouse Ccl11 gene that encode the full-length protein were replaced by human CCL11 exons 1-3 in B-hCCL11 mice.

Protein expression analysis

Strain specific CCL11 expression analysis in homozygous B-hCCL11 mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hCCL11 mice (H/H), and analyzed by ELISA with species-specific CCL11 ELISA kit. Mouse CCL11 was detectable only in wild-type mice. Human CCL11 was detectable in homozygous B-hCCL11 mice but not in wild-type mice.

* When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hCCL11 mice] (Cat# 111404) was purchased from Biocytogen.

B-hCCL11 mice

B-hCCL11 mice

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Targeting strategy

Protein expression analysis