Name: B-NDG hB2M/HLA-A11.1 mice
Brand: Biocytogen
SKU: 112451

B-NDG hB2M/HLA-A11.1 mice

Catalog Number: 112451

Strain Name: NOD.CB17-Prkdc^scidIl2rg^{tm1 Bcgen}B2m^{tm1(B2M/HLA-A11.1)Bcgen}/Bcgen

Strain Background: B-NDG

NCBI gene ID: 19090,16186,12010,14972,14964 (Human)

Aliases: p460; scid; slip; DNAPK; DNPK1; HYRC1; XRCC7; dxnph; DOXNPH; DNAPDcs; DNA-PKcs; gc; p64; [g]c; CD132; gamma(c); Ly-m11; beta2m; beta2-m; K-f; H-2K; H2-K; H2-D1; H-2K(d); H-2D; H2-D; H2-K1

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Protein expression analysis

B2M and HLA-A11.1 expression analysis in homozygous B-NDG hB2M/HLA-A11.1 mice by flow cytometry. Splenocytes were collected from B-NDG mice (+/+) and homozygous B-NDG hB2M/HLA-A11.1 mice (H/H), and analyzed by flow cytometry with strain specific antibodies. Mouse B2M was detectable in B-NDG mice but not in B-NDG hB2M/HLA-A11.1 mice. Human B2M and HLA-ABC were exclusively detectable in homozygous B-NDG hB2M/HLA-A11.1 mice but not in B-NDG mice.

* When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-NDG hB2M/HLA-A11.1 mice] (Cat# 112451) was purchased from Biocytogen.

B-NDG hB2M/HLA-A11.1 mice

B-NDG hB2M/HLA-A11.1 mice

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Protein expression analysis